Lyra Therapeutics Key Executives

This section highlights Lyra Therapeutics's key executives, including their titles and compensation details.

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Lyra Therapeutics Earnings

This section highlights Lyra Therapeutics's earnings, including key dates, EPS, earnings reports, and earnings call transcripts.

Next Earnings Date

Date: April 29, 2025
Time: Before Market
Est. EPS: $-0.15
Status: Unconfirmed

Last Earnings Results

Date: March 13, 2025
EPS: $-0.16
Est. EPS: $-0.13
Revenue: $209.00K

Earnings Call Transcripts

Transcript Quarter Year Date Estimated EPS Actual EPS

Lyra Therapeutics, Inc. (LYRA)

Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.

Healthcare Biotechnology

$0.15

Stock Price

$9.90M

Market Cap

87

Employees

Watertown, MA

Location

Financial Statements

Access annual & quarterly financial statements for Lyra Therapeutics, including income statements, balance sheets, and cash flow statements..

Annual Income Statement

Breakdown December 31, 2024 December 31, 2023 December 31, 2022 December 31, 2021 December 31, 2020
Revenue $1.53M $1.56M $1.36M $285.00K $-
Cost of Revenue $- $- $1.07M $1.00M $95.00K
Gross Profit $1.53M $1.56M $296.00K $-716.00K $-95.00K
Gross Profit Ratio 100.00% 100.00% 21.72% -251.20% 0.00%
Research and Development Expenses $43.77M $48.03M $38.80M $29.69M $12.52M
General and Administrative Expenses $18.50M $19.06M $17.56M $14.21M $9.69M
Selling and Marketing Expenses $- $- $- $- $-
Selling General and Administrative Expenses $18.50M $19.06M $17.56M $14.21M $9.69M
Other Expenses $35.62M $- $1.32M $- $-
Operating Expenses $97.88M $68.68M $56.35M $43.90M $22.21M
Cost and Expenses $97.88M $68.68M $56.35M $43.90M $22.21M
Interest Income $2.95M $4.50M $1.04M $102.00K $82.00K
Interest Expense $- $- $524.00K $- $-
Depreciation and Amortization $471.00K $278.00K $1.07M $1.00M $95.00K
EBITDA $-60.26M $-65.25M $-53.92M $-42.61M $-22.11M
EBITDA Ratio -3928.42% -4188.06% -3937.93% -15303.51% 0.00%
Operating Income $-96.35M $-67.12M $-56.31M $-43.62M $-22.21M
Operating Income Ratio -6280.83% -4308.09% -4131.03% -15303.51% 0.00%
Total Other Income Expenses Net $2.95M $4.50M $1.04M $102.00K $82.00K
Income Before Tax $-93.40M $-62.62M $-55.27M $-43.51M $-22.13M
Income Before Tax Ratio -6088.40% -4019.32% -4054.66% -15267.72% 0.00%
Income Tax Expense $39.00K $59.00K $13.00K $-1.10M $-82.00K
Net Income $-93.44M $-62.68M $-55.28M $-42.41M $-22.05M
Net Income Ratio -6090.94% -4023.11% -4055.61% -14880.70% 0.00%
EPS $-1.43 $-1.26 $-1.83 $-3.27 $-2.57
EPS Diluted $-1.43 $-1.26 $-1.83 $-3.27 $-2.57
Weighted Average Shares Outstanding 65.11M 49.80M 30.24M 12.99M 8.59M
Weighted Average Shares Outstanding Diluted 65.11M 49.80M 30.24M 12.99M 8.59M
SEC Filing Source Source Source Source Source


Breakdown December 31, 2024 September 30, 2024 June 30, 2024 March 31, 2024 December 31, 2023 September 30, 2023 June 30, 2023 March 31, 2023 December 31, 2022 September 30, 2022 June 30, 2022 March 31, 2022 December 31, 2021 September 30, 2021 June 30, 2021 March 31, 2021 December 31, 2020 September 30, 2020 June 30, 2020 March 31, 2020
Revenue $209.00K $195.00K $598.00K $532.00K $146.00K $544.00K $458.00K $410.00K $11.00K $359.00K $407.00K $5.37M $271.00K $14.00K $- $- $- $- $- $-
Cost of Revenue $- $- $13.26M $136.00K $85.00K $12.37M $10.80M $284.00K $222.00K $- $300.00K $280.00K $14.00K $6.38M $300.00K $70.00K $3.74M $3.71M $- $-
Gross Profit $209.00K $195.00K $-12.67M $396.00K $61.00K $-11.82M $-10.34M $126.00K $-211.00K $359.00K $107.00K $5.09M $257.00K $-6.36M $-300.00K $-70.00K $-3.74M $-3.71M $- $-
Gross Profit Ratio 100.00% 100.00% -2118.10% 74.40% 41.80% -2173.50% -2257.90% 30.70% -1918.20% 100.00% 26.30% 94.80% 94.80% -45450.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Research and Development Expenses $6.36M $5.90M $13.26M $18.10M $12.18M $12.37M $10.80M $12.60M $9.45M $10.05M $10.79M $8.51M $10.34M $7.08M $7.50M $4.77M $3.74M $3.71M $2.10M $2.96M
General and Administrative Expenses $3.61M $3.93M $5.14M $5.82M $4.36M $5.00M $4.57M $5.13M $4.40M $5.14M $4.13M $3.89M $3.57M $4.02M $3.56M $3.06M $3.31M $2.65M $2.44M $1.28M
Selling and Marketing Expenses $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Selling General and Administrative Expenses $3.61M $3.93M $5.14M $5.82M $4.36M $5.00M $4.57M $5.13M $4.40M $5.14M $4.13M $3.89M $3.57M $4.02M $3.56M $3.06M $3.31M $2.65M $2.44M $1.28M
Other Expenses $1.64M $2.80M $29.29M $- $- $- $1.59M $- $1.32M $- $- $- $- $- $- $- $- $- $- $-
Operating Expenses $11.62M $12.64M $18.26M $23.92M $16.54M $17.37M $15.37M $17.72M $13.85M $15.19M $14.93M $12.39M $13.91M $11.10M $11.06M $7.83M $7.05M $6.36M $4.54M $4.25M
Cost and Expenses $11.62M $12.64M $18.40M $24.06M $16.62M $17.37M $15.37M $17.72M $13.85M $15.19M $14.93M $12.39M $13.91M $11.10M $11.06M $7.83M $7.05M $6.36M $4.54M $4.25M
Interest Income $435.00K $576.00K $855.00K $1.09M $1.34M $1.19M $897.00K $1.07M $933.00K $60.00K $34.00K $14.00K $21.00K $26.00K $26.00K $29.00K $32.00K $29.00K $5.00K $16.00K
Interest Expense $- $- $- $- $1.07M $- $- $- $12.00K $- $34.00K $- $257.00K $- $- $- $50.00K $- $- $-
Depreciation and Amortization $151.00K $39.00K $145.00K $136.00K $85.00K $-68.00K $-23.00K $284.00K $222.00K $279.00K $300.00K $280.00K $278.00K $400.00K $300.00K $70.00K $41.00K $33.00K $13.00K $8.00K
EBITDA $-9.62M $-9.60M $-17.66M $-23.39M $-16.39M $-16.83M $-14.91M $-17.03M $-13.62M $-14.55M $-14.11M $-11.64M $-13.36M $-10.73M $-10.76M $-7.76M $-7.01M $-6.33M $-4.53M $-4.24M
EBITDA Ratio -4600.48% -4922.56% -2953.18% -4396.24% -11227.40% -3093.20% -2908.08% -4153.41% -123790.91% -4052.09% -3496.81% -125.69% -4929.89% -76650.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Operating Income $-11.41M $-12.44M $-48.97M $-23.52M $-16.48M $-16.83M $-16.50M $-17.31M $-15.15M $-14.83M $-14.52M $-7.03M $-13.64M $-11.08M $-11.06M $-7.83M $-7.05M $-6.36M $-4.54M $-4.25M
Operating Income Ratio -5458.37% -6380.51% -8189.63% -4421.80% -11285.62% -3093.20% -3603.28% -4222.68% -137772.73% -4129.81% -3567.08% -130.91% -5032.47% -79150.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Total Other Income Expenses Net $435.00K $576.00K $855.00K $1.09M $1.34M $1.19M $897.00K $1.07M $933.00K $60.00K $34.00K $14.00K $21.00K $26.00K $26.00K $29.00K $32.00K $29.00K $5.00K $16.00K
Income Before Tax $-10.97M $-11.87M $-48.12M $-22.44M $-15.14M $-15.63M $-15.61M $-16.24M $-14.22M $-14.77M $-14.48M $-7.01M $-13.62M $-11.05M $-11.04M $-7.80M $-7.02M $-6.33M $-4.54M $-4.23M
Income Before Tax Ratio -5250.24% -6085.13% -8046.66% -4217.67% -10369.18% -2874.08% -3407.42% -3961.22% -129290.91% -4113.09% -3558.72% -130.65% -5024.72% -78964.29% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Income Tax Expense $6.00K $7.00K $12.00K $14.00K $17.00K $-16.00K $12.00K $14.00K $13.00K $- $-68.00K $-14.00K $-278.00K $-26.00K $-26.00K $-29.00K $-32.00K $-29.00K $-5.00K $-16.00K
Net Income $-10.98M $-11.87M $-48.13M $-22.45M $-15.16M $-15.65M $-15.62M $-16.25M $-14.23M $-14.77M $-14.42M $-7.00M $-13.34M $-11.05M $-11.04M $-7.80M $-7.02M $-6.33M $-4.54M $-4.23M
Net Income Ratio -5253.11% -6088.72% -8048.66% -4220.30% -10380.82% -2877.02% -3410.04% -3964.63% -129409.09% -4113.09% -3542.01% -130.39% -4922.14% -78964.29% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EPS $-0.18 $-0.18 $-0.74 $-0.35 $-0.26 $-0.27 $-0.36 $-0.44 $-0.45 $-0.40 $-0.42 $-0.54 $-1.03 $-0.85 $-0.85 $-0.60 $-0.57 $-0.49 $-0.55 $-0.34
EPS Diluted $-0.18 $-0.18 $-0.74 $-0.35 $-0.26 $-0.27 $-0.36 $-0.44 $-0.45 $-0.40 $-0.42 $-0.54 $-1.03 $-0.85 $-0.85 $-0.60 $-0.57 $-0.49 $-0.55 $-0.34
Weighted Average Shares Outstanding 65.46M 65.46M 65.46M 64.01M 57.21M 56.95M 43.68M 36.83M 31.83M 36.83M 33.95M 13.01M 12.97M 13.00M 12.99M 12.95M 12.40M 12.92M 8.18M 12.38M
Weighted Average Shares Outstanding Diluted 65.46M 65.46M 65.46M 64.01M 57.21M 56.95M 43.68M 36.83M 31.83M 36.83M 33.95M 13.01M 13.00M 13.00M 12.99M 12.95M 12.40M 12.92M 8.18M 12.38M
SEC Filing Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source Source

Annual Balance Sheet

Breakdown December 31, 2024 December 31, 2023 December 31, 2022 December 31, 2021 December 31, 2020
Cash and Cash Equivalents $40.58M $22.35M $32.55M $45.75M $74.59M
Short Term Investments $- $80.40M $65.34M $- $-
Cash and Short Term Investments $40.58M $102.75M $97.89M $45.75M $74.59M
Net Receivables $- $- $- $- $-
Inventory $- $- $- $- $-
Other Current Assets $2.45M $2.07M $2.94M $4.34M $2.65M
Total Current Assets $43.02M $104.82M $100.83M $47.92M $75.92M
Property Plant Equipment Net $21.33M $35.28M $4.47M $5.86M $4.47M
Goodwill $- $- $- $- $-
Intangible Assets $- $- $- $- $-
Goodwill and Intangible Assets $- $- $- $- $-
Long Term Investments $- $- $1.39M $329.00K $329.00K
Tax Assets $- $- $- $- $-
Other Non-Current Assets $1.99M $2.50M $3.28M $762.00K $118.00K
Total Non-Current Assets $23.32M $37.78M $9.14M $6.95M $4.91M
Other Assets $- $- $- $- $-
Total Assets $66.35M $142.60M $109.97M $54.87M $80.83M
Account Payables $1.18M $3.13M $2.62M $3.12M $922.00K
Short Term Debt $4.12M $8.91M $3.51M $2.15M $1.97M
Tax Payables $- $- $- $- $-
Deferred Revenue $398.00K $1.66M $1.27M $9.79M $2.83M
Other Current Liabilities $6.93M $9.37M $9.03M $3.18M $1.99M
Total Current Liabilities $12.63M $19.60M $14.47M $18.25M $4.88M
Long Term Debt $30.26M $21.45M $667.00K $379.00K $1.45M
Deferred Revenue Non-Current $- $12.14M $14.08M $1.93M $-
Deferred Tax Liabilities Non-Current $- $- $-14.08M $-1.93M $-
Other Non-Current Liabilities $11.86M $- $- $- $-
Total Non-Current Liabilities $42.12M $33.58M $14.74M $2.31M $1.45M
Other Liabilities $- $- $- $- $-
Total Liabilities $54.75M $53.18M $29.21M $20.55M $6.34M
Preferred Stock $- $- $- $- $80.83M
Common Stock $65.00K $57.00K $32.00K $13.00K $13.00K
Retained Earnings $-404.79M $-311.36M $-248.68M $-193.40M $-149.88M
Accumulated Other Comprehensive Income Loss $- $33.00K $10.00K $- $-80.83M
Other Total Stockholders Equity $416.32M $400.69M $329.39M $227.70M $305.19M
Total Stockholders Equity $11.59M $89.42M $80.75M $34.32M $74.49M
Total Equity $11.59M $89.42M $80.75M $34.32M $74.49M
Total Liabilities and Stockholders Equity $66.35M $142.60M $109.97M $54.87M $80.83M
Minority Interest $- $- $- $- $-
Total Liabilities and Total Equity $66.35M $142.60M $109.97M $54.87M $80.83M
Total Investments $- $80.40M $65.34M $329.00K $329.00K
Total Debt $34.38M $26.88M $2.22M $1.45M $2.44M
Net Debt $-6.20M $4.53M $-30.33M $-44.29M $-72.15M


Balance Sheet Charts

Breakdown December 31, 2024 September 30, 2024 June 30, 2024 March 31, 2024 December 31, 2023 September 30, 2023 June 30, 2023 March 31, 2023 December 31, 2022 September 30, 2022 June 30, 2022 March 31, 2022 December 31, 2021 September 30, 2021 June 30, 2021 March 31, 2021 December 31, 2020 September 30, 2020 June 30, 2020 March 31, 2020
Cash and Cash Equivalents $40.58M $23.80M $31.91M $15.80M $22.35M $24.85M $54.36M $22.02M $32.55M $109.56M $120.67M $33.76M $45.75M $58.13M $69.05M $66.11M $74.59M $81.56M $86.60M $35.25M
Short Term Investments $- $27.83M $35.59M $71.32M $80.40M $77.70M $61.79M $60.69M $65.34M $- $- $- $- $- $- $- $- $- $- $-
Cash and Short Term Investments $40.58M $51.63M $67.50M $87.12M $102.75M $102.55M $116.15M $82.71M $97.89M $109.56M $120.67M $33.76M $45.75M $58.13M $69.05M $66.11M $74.59M $81.56M $86.60M $35.25M
Net Receivables $- $- $- $- $- $- $- $- $- $- $- $5.00M $- $- $- $- $- $- $- $-
Inventory $- $- $- $- $- $- $- $- $- $- $- $1 $- $- $- $- $- $- $- $-
Other Current Assets $2.45M $2.82M $1.94M $2.33M $2.07M $2.37M $3.90M $2.09M $2.94M $2.67M $1.71M $1.80M $4.34M $5.51M $2.05M $1.25M $2.65M $4.00M $5.42M $586.00K
Total Current Assets $43.02M $54.44M $69.44M $89.44M $104.82M $104.92M $118.25M $84.80M $100.83M $112.23M $122.38M $40.55M $47.92M $60.89M $70.07M $67.35M $75.92M $83.56M $89.31M $35.54M
Property Plant Equipment Net $21.33M $22.32M $23.16M $49.41M $35.28M $6.80M $1.98M $3.83M $4.47M $4.36M $4.87M $5.38M $5.86M $6.30M $5.69M $5.24M $4.47M $3.45M $3.08M $3.25M
Goodwill $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Intangible Assets $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Goodwill and Intangible Assets $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Long Term Investments $- $- $- $1.99M $1.39M $1.39M $1.09M $1.39M $1.39M $- $1.09M $329.00K $329.00K $329.00K $329.00K $329.00K $- $- $- $-
Tax Assets $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Other Non-Current Assets $1.99M $1.99M $1.99M $683.00K $1.11M $7.46M $4.35M $3.85M $3.28M $2.87M $1.70M $1.08M $762.00K $245.00K $243.00K $- $447.00K $329.00K $329.00K $1.98M
Total Non-Current Assets $23.32M $24.31M $25.15M $52.08M $37.78M $15.65M $7.42M $9.07M $9.14M $7.23M $7.65M $6.79M $6.95M $6.88M $6.26M $5.57M $4.91M $3.77M $3.41M $5.23M
Other Assets $- $- $- $1 $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Total Assets $66.35M $78.76M $94.58M $141.53M $142.60M $120.58M $125.67M $93.87M $109.97M $119.46M $130.03M $47.34M $54.87M $67.76M $76.33M $72.92M $80.83M $87.33M $92.72M $40.77M
Account Payables $1.18M $2.29M $4.97M $2.84M $3.13M $5.05M $4.19M $3.95M $2.62M $2.90M $1.67M $2.41M $3.12M $2.91M $1.90M $1.17M $922.00K $530.00K $1.15M $1.36M
Short Term Debt $4.12M $4.00M $8.54M $4.50M $10.87M $2.81M $3.38M $3.80M $3.51M $1.31M $1.85M $2.19M $1.07M $2.10M $1.03M $1.01M $985.00K $1.93M $1.89M $1.84M
Tax Payables $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Deferred Revenue $398.00K $607.00K $814.00K $1.32M $1.66M $1.73M $1.50M $1.51M $1.27M $2.73M $1.81M $10.06M $9.79M $9.84M $12.00M $1.93M $2.83M $3.10M $1.74M $2.73M
Other Current Liabilities $6.93M $8.05M $4.95M $10.06M $3.94M $9.65M $5.05M $4.89M $9.03M $6.67M $4.54M $3.14M $4.26M $2.92M $2.98M $1.99M $2.98M $2.25M $910.00K $1.96M
Total Current Liabilities $12.63M $14.95M $19.28M $18.72M $19.60M $19.23M $14.11M $14.15M $14.47M $13.61M $9.87M $17.80M $18.25M $17.77M $5.90M $4.17M $4.88M $4.71M $3.94M $5.16M
Long Term Debt $30.26M $31.32M $32.48M $33.36M $21.45M $4.89M $- $191.00K $667.00K $3.00K $3.00K $99.00K $379.00K $656.00K $929.00K $1.20M $1.45M $1.71M $1.96M $2.19M
Deferred Revenue Non-Current $11.86M $11.86M $11.85M $11.94M $12.14M $12.21M $12.99M $13.43M $14.08M $12.63M $9.13M $1.29M $1.93M $2.15M $12.00M $- $- $- $- $-
Deferred Tax Liabilities Non-Current $- $- $- $-11.94M $-21.45M $-12.21M $- $-13.43M $-14.08M $-12.63M $-9.13M $-2.02M $-1.93M $-2.15M $-12.00M $- $- $- $- $-
Other Non-Current Liabilities $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $160.20M
Total Non-Current Liabilities $42.12M $43.18M $44.33M $45.30M $33.58M $17.10M $12.99M $13.62M $14.74M $12.64M $9.13M $1.39M $2.31M $2.80M $12.93M $1.20M $1.45M $1.71M $1.96M $162.39M
Other Liabilities $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Total Liabilities $54.75M $58.14M $63.60M $64.02M $53.18M $36.34M $27.10M $27.78M $29.21M $26.24M $19.00M $19.19M $20.55M $20.57M $18.83M $5.37M $6.34M $6.42M $5.90M $167.55M
Preferred Stock $- $- $- $- $- $- $- $- $- $- $0 $- $- $- $0 $- $0 $87.33M $92.72M $39.74M
Common Stock $65.00K $65.00K $65.00K $61.00K $57.00K $50.00K $50.00K $32.00K $32.00K $32.00K $32.00K $13.00K $13.00K $13.00K $13.00K $13.00K $13.00K $13.00K $13.00K $-
Retained Earnings $-404.79M $-393.81M $-381.94M $-333.81M $-311.36M $-296.20M $-280.55M $-264.93M $-248.68M $-234.44M $-214.89M $-200.41M $-193.40M $-179.78M $-168.72M $-157.69M $-149.88M $-142.86M $-136.53M $-131.99M
Accumulated Other Comprehensive Income Loss $- $20.00K $-4.00K $25.00K $33.00K $-7.00K $-27.00K $-12.00K $10.00K $- $-0 $- $- $- $-0 $0 $-0 $-87.33M $-2.85M $-2.84M
Other Total Stockholders Equity $416.32M $414.35M $412.85M $411.23M $400.69M $380.39M $379.10M $331.00M $329.39M $327.63M $325.89M $228.55M $227.70M $226.96M $226.21M $225.22M $224.36M $223.76M $223.34M $-34.53M
Total Stockholders Equity $11.59M $20.62M $30.98M $77.50M $89.42M $84.24M $98.58M $66.09M $80.75M $93.22M $111.03M $28.16M $34.32M $47.19M $57.50M $67.55M $74.49M $80.91M $86.82M $-126.78M
Total Equity $11.59M $20.62M $30.98M $77.50M $89.42M $84.24M $98.58M $66.09M $80.75M $93.22M $111.03M $28.16M $34.32M $47.19M $57.50M $67.55M $74.49M $80.91M $86.82M $-126.78M
Total Liabilities and Stockholders Equity $66.35M $78.76M $94.58M $141.53M $142.60M $120.58M $125.67M $93.87M $109.97M $119.46M $130.03M $47.34M $54.87M $67.76M $76.33M $72.92M $80.83M $87.33M $92.72M $40.77M
Minority Interest $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Total Liabilities and Total Equity $66.35M $78.76M $94.58M $141.53M $142.60M $120.58M $125.67M $93.87M $109.97M $119.46M $130.03M $47.34M $54.87M $67.76M $76.33M $72.92M $80.83M $87.33M $92.72M $40.77M
Total Investments $- $27.83M $35.59M $73.31M $81.79M $77.70M $61.79M $60.69M $65.34M $- $1.09M $329.00K $329.00K $329.00K $329.00K $329.00K $- $- $- $-
Total Debt $34.38M $35.32M $36.75M $37.86M $26.88M $6.29M $1.69M $2.09M $2.22M $657.00K $929.00K $1.20M $1.45M $1.71M $1.96M $2.20M $2.44M $2.67M $2.90M $3.11M
Net Debt $-6.20M $11.52M $4.84M $22.06M $4.53M $-18.56M $-52.67M $-19.93M $-30.33M $-108.90M $-119.74M $-32.56M $-44.29M $-56.42M $-67.09M $-63.90M $-72.15M $-78.88M $-83.70M $-32.14M

Annual Cash Flow

Breakdown December 31, 2024 December 31, 2023 December 31, 2022 December 31, 2021 December 31, 2020
Net Income $-93.44M $-62.68M $-55.28M $-43.51M $-22.13M
Depreciation and Amortization $471.00K $278.00K $1.07M $1.00M $95.00K
Deferred Income Tax $- $- $- $-2.42M $-
Stock Based Compensation $6.72M $5.89M $5.45M $2.77M $1.81M
Change in Working Capital $-6.35M $-4.88M $4.55M $13.92M $-879.00K
Accounts Receivables $- $- $- $- $-
Inventory $- $- $- $- $-
Accounts Payables $-1.89M $450.00K $-2.41M $2.35M $345.00K
Other Working Capital $-4.46M $-5.33M $6.97M $11.57M $-1.22M
Other Non Cash Items $22.58M $-1.90M $824.00K $2.42M $-45.00K
Net Cash Provided by Operating Activities $-70.01M $-63.30M $-43.38M $-25.82M $-21.14M
Investments in Property Plant and Equipment $-2.34M $-1.05M $-164.00K $-3.38M $-1.77M
Acquisitions Net $- $- $- $- $-
Purchases of Investments $-47.95M $-122.42M $-64.84M $- $-
Sales Maturities of Investments $130.59M $110.89M $- $- $-
Other Investing Activities $- $-1 $-64.84M $- $-
Net Cash Used for Investing Activities $80.31M $-12.58M $-65.01M $-3.38M $-1.77M
Debt Repayment $- $- $- $- $-
Common Stock Issued $8.82M $69.24M $100.50M $604.00K $59.89M
Common Stock Repurchased $- $- $- $- $-
Dividends Paid $- $- $- $- $-
Other Financing Activities $-287.00K $-3.55M $-4.24M $359.00K $27.81M
Net Cash Used Provided by Financing Activities $8.53M $65.69M $96.26M $359.00K $87.70M
Effect of Forex Changes on Cash $- $- $- $- $-
Net Change in Cash $18.82M $-10.20M $-12.13M $-28.85M $64.78M
Cash at End of Period $42.57M $23.75M $33.94M $46.08M $74.92M
Cash at Beginning of Period $23.75M $33.94M $46.08M $74.92M $10.14M
Operating Cash Flow $-70.01M $-63.30M $-43.38M $-25.82M $-21.14M
Capital Expenditure $-2.34M $-1.05M $-164.00K $-3.38M $-1.77M
Free Cash Flow $-72.35M $-64.35M $-43.55M $-29.20M $-22.92M

Cash Flow Charts

Breakdown December 31, 2024 September 30, 2024 June 30, 2024 March 31, 2024 December 31, 2023 September 30, 2023 June 30, 2023 March 31, 2023 December 31, 2022 September 30, 2022 June 30, 2022 March 31, 2022 December 31, 2021 September 30, 2021 June 30, 2021 March 31, 2021 December 31, 2020 September 30, 2020 June 30, 2020 March 31, 2020
Net Income $-10.98M $-11.87M $-48.13M $-22.45M $-15.16M $-15.65M $-15.62M $-16.25M $-14.23M $-19.55M $-14.48M $-7.01M $-13.62M $-11.05M $-11.04M $-7.80M $-7.02M $-6.33M $-4.54M $-4.23M
Depreciation and Amortization $151.00K $-1.97M $145.00K $136.00K $85.00K $-68.00K $-23.00K $284.00K $222.00K $279.00K $286.00K $280.00K $278.00K $350.00K $303.00K $70.00K $41.00K $33.00K $13.00K $8.00K
Deferred Income Tax $- $- $- $- $-5.19M $- $- $- $- $- $-2.67M $- $-13.92M $- $- $- $879.00K $- $- $-
Stock Based Compensation $1.94M $1.49M $1.12M $2.16M $1.48M $1.44M $1.35M $1.61M $1.76M $1.74M $1.11M $844.00K $782.00K $733.00K $656.00K $599.00K $592.00K $468.00K $619.00K $134.00K
Change in Working Capital $-2.20M $-1.33M $2.70M $-1.37M $-4.38M $1.22M $-961.00K $-763.00K $-732.00K $6.68M $4.62M $-6.02M $1.26M $-342.00K $13.46M $-457.00K $520.00K $2.10M $-3.57M $73.00K
Accounts Receivables $- $- $- $- $- $- $- $- $5.00M $- $5.00M $-5.00M $- $- $- $- $- $- $- $-
Inventory $- $- $- $- $- $- $- $- $- $- $-5.00M $- $- $- $- $- $- $- $- $-
Accounts Payables $-1.11M $-2.59M $2.38M $-560.00K $-3.54M $796.00K $-106.00K $3.29M $-2.24M $1.47M $-976.00K $-663.00K $1.18M $424.00K $291.00K $452.00K $204.00K $3.00K $-294.00K $432.00K
Other Working Capital $-1.08M $1.26M $319.00K $-808.00K $-846.00K $424.00K $-855.00K $-4.06M $-3.49M $4.42M $5.60M $-354.00K $77.00K $-766.00K $13.17M $-909.00K $316.00K $2.10M $-3.28M $-359.00K
Other Non Cash Items $-267.00K $-2.54M $24.18M $2.06M $4.10M $-1.06M $966.00K $-726.00K $824.00K $1.11M $2.67M $7.07M $13.92M $1.06M $968.00K $287.00K $-879.00K $-45.00K $-294.00K $432.00K
Net Cash Provided by Operating Activities $-11.35M $-16.22M $-19.98M $-22.45M $-19.06M $-14.11M $-14.28M $-15.85M $-12.16M $-10.85M $-8.47M $-11.90M $-11.30M $-10.31M $3.38M $-7.59M $-5.87M $-3.78M $-7.48M $-4.02M
Investments in Property Plant and Equipment $58.00K $-51.00K $-196.00K $-2.15M $-787.00K $-144.00K $-71.00K $-45.00K $-28.00K $-29.00K $-14.00K $-93.00K $-1.08M $-517.00K $-625.00K $-1.16M $-1.10M $-589.00K $-77.00K $-8.00K
Acquisitions Net $- $- $- $- $-9.96M $14.84M $490.00K $-5.36M $- $- $- $- $- $- $- $- $- $- $- $-
Purchases of Investments $- $-12.81M $-14.62M $-20.52M $-49.66M $-42.84M $-25.49M $-4.44M $-64.84M $- $- $- $- $- $- $- $- $- $- $-
Sales Maturities of Investments $28.07M $21.00M $50.99M $30.53M $48.09M $28.00M $25.00M $9.80M $- $- $- $- $- $- $- $- $- $- $- $-
Other Investing Activities $- $- $- $10.01M $-1.57M $-14.84M $-490.00K $5.36M $-64.84M $- $- $- $- $- $- $- $- $- $- $-
Net Cash Used for Investing Activities $28.13M $8.14M $36.18M $7.86M $-2.36M $-14.98M $-561.00K $5.32M $-64.87M $-29.00K $-14.00K $-93.00K $-1.08M $-517.00K $-625.00K $-1.16M $-1.10M $-589.00K $-77.00K $-8.00K
Debt Repayment $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Common Stock Issued $-1.00K $-3.00K $9.00K $8.81M $19.24M $2.00K $50.10M $4.00K $100.50M $- $- $8.00K $604.00K $11.00K $331.00K $262.00K $30.39M $- $- $30.39M
Common Stock Repurchased $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Dividends Paid $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $- $-
Other Financing Activities $- $-23.00K $-89.00K $8.64M $-322.00K $-418.00K $47.19M $4.00K $-196.99M $-236.00K $96.49M $6.00K $-4.00K $-84.00K $185.00K $262.00K $7.00K $-675.00K $58.91M $29.46M
Net Cash Used Provided by Financing Activities $-1.00K $-23.00K $-89.00K $8.64M $18.92M $-418.00K $47.19M $4.00K $-96.49M $-236.00K $96.49M $6.00K $-4.00K $-84.00K $185.00K $262.00K $7.00K $-675.00K $58.91M $29.46M
Effect of Forex Changes on Cash $- $- $- $- $- $- $- $- $96.49M $- $- $- $- $- $- $- $- $- $- $-
Net Change in Cash $16.78M $-8.11M $16.11M $-6.55M $-2.50M $-29.51M $32.34M $-10.53M $-77.03M $-11.11M $88.00M $-11.99M $-12.38M $-10.91M $2.94M $-8.49M $-6.96M $-5.04M $51.35M $25.44M
Cash at End of Period $42.57M $25.79M $31.91M $15.80M $22.35M $26.24M $55.75M $23.41M $33.94M $110.98M $122.09M $34.08M $46.08M $58.46M $69.38M $66.43M $74.92M $81.88M $86.93M $35.58M
Cash at Beginning of Period $25.79M $33.90M $15.80M $22.35M $24.85M $55.75M $23.41M $33.94M $110.98M $122.09M $34.08M $46.08M $58.46M $69.38M $66.43M $74.92M $81.88M $86.93M $35.58M $10.14M
Operating Cash Flow $-11.35M $-16.22M $-19.98M $-22.45M $-19.06M $-14.11M $-14.28M $-15.85M $-12.16M $-10.85M $-8.47M $-11.90M $-11.30M $-10.31M $3.38M $-7.59M $-5.87M $-3.78M $-7.48M $-4.02M
Capital Expenditure $58.00K $-51.00K $-196.00K $-2.15M $-787.00K $-144.00K $-71.00K $-45.00K $-28.00K $-29.00K $-14.00K $-93.00K $-1.08M $-517.00K $-625.00K $-1.16M $-1.10M $-589.00K $-77.00K $-8.00K
Free Cash Flow $-11.29M $-16.27M $-20.18M $-24.60M $-19.84M $-14.26M $-14.35M $-15.89M $-12.19M $-10.88M $-8.48M $-12.00M $-12.38M $-10.83M $2.76M $-8.75M $-6.97M $-4.37M $-7.55M $-4.03M

Lyra Therapeutics Dividends

Explore Lyra Therapeutics's dividend history, including dividend yield, payout ratio, and historical payments.

Lyra Therapeutics does not currently pay a dividend.

Lyra Therapeutics News

Read the latest news about Lyra Therapeutics, including recent articles, headlines, and updates.

Lyra Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update

WATERTOWN, Mass., March 13, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc.  (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today reported its financial results for the fourth quarter and full year ended December 31, 2024 and provided a corporate update.

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Lyra Therapeutics (LYRA) Upgraded to Strong Buy: Here's What You Should Know

Lyra Therapeutics (LYRA) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #1 (Strong Buy).

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Lyra Therapeutics, Inc. (LYRA) Reports Q3 Loss, Lags Revenue Estimates

Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.18 per share versus the Zacks Consensus Estimate of a loss of $0.23. This compares to loss of $0.27 per share a year ago.

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Lyra Therapeutics Reports Third Quarter 2024 Financial Results and Provides Corporate Update

WATERTOWN, Mass., Nov. 12, 2024 (GLOBE NEWSWIRE) --   Lyra Therapeutics, Inc.  (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today reported its financial results for the third quarter ended September 30, 2024 and provided a corporate update.

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Lyra Therapeutics Fully Enrolls Pivotal Phase 3 ENLIGHTEN 2 Trial of LYR-210 for the Treatment of Chronic Rhinosinusitis

-- Topline Results Expected Q2 2025 -- WATERTOWN, Mass., Oct. 15, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting anti-inflammatory therapies for the localized treatment of chronic rhinosinusitis (CRS), today announced that the pivotal Phase 3 ENLIGHTEN 2 clinical trial of LYR-210 in adult patients with CRS who have not had prior ethmoid sinus surgery, is fully enrolled. LYR-210 is a bioresorbable nasal implant designed to deliver six months of continuous anti-inflammatory medication (mometasone furoate) to the sinonasal passages for the treatment of CRS. Topline results from ENLIGHTEN 2 are expected in Q2 2025.

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Lyra Therapeutics to Present Study Results for LYR-210 and LYR-220 in Two Presentations at the ARS and AAO-HNS Annual Meetings

WATERTOWN, Mass., Sept. 27, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA), (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting anti-inflammatory therapies for the localized treatment of chronic rhinosinusitis (CRS), today announced that the Company will present results from the Phase 3 ENLIGHTEN 1 study for LYR-210, the company's lead product candidate for CRS, at the 70th Annual Meeting of the American Rhinologic Society (ARS), taking place September 27-28 in Miami. The Company will also present additional results from the Phase 2 BEACON study for LYR-220 in adult patients with CRS who have had prior ethmoid sinus surgery at the Annual Meeting of the American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS), taking place September 28 - October 1 in Miami.

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Lyra Therapeutics, Inc. (LYRA) Reports Q2 Loss, Tops Revenue Estimates

Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.29 per share versus the Zacks Consensus Estimate of a loss of $0.34. This compares to loss of $0.33 per share a year ago.

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Lyra Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update

– Primary focus continues to be on upcoming results from ENLIGHTEN 1 Phase 3 extension study in 4Q 2024 and ENLIGHTEN 2 pivotal Phase 3 trial in CRS patients in 1H 2025, as planned –

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Lyra Therapeutics Announces Cost-Cutting Measures to Preserve Capital

WATERTOWN, Mass., May 21, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), today announced that it is advancing its goal to preserve capital by implementing a layoff of approximately 75% of its workforce, in addition to other cost-cutting measures.

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Why Is Lyra Therapeutics (LYRA) Stock Down 90% Today?

Lyra Therapeutics (NASDAQ: LYRA ) stock is falling hard on Monday after the clinical-stage biotechnology company announced results from a Phase 3 clinical trial of LYR-210. LYR-210 is the company's potential treatment for chronic rhinosinusitis currently in development.

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Lyra Therapeutics Reports Topline Results from Phase 3 ENLIGHTEN 1 Trial for LYR-210 in Chronic Rhinosinusitis

ENLIGHTEN 1 trial did not meet its primary endpoint Company plans to evaluate full dataset and path forward WATERTOWN, Mass., May 06, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), today announced topline results from the Company's Phase 3 ENLIGHTEN 1 trial evaluating LYR-210 for the treatment of chronic rhinosinusitis (CRS).

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Lyra Therapeutics, Inc. (LYRA) Reports Q1 Loss, Tops Revenue Estimates

Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.35 per share versus the Zacks Consensus Estimate of a loss of $0.26. This compares to loss of $0.44 per share a year ago.

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Lyra Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update

-- Phase 3 Results from ENLIGHTEN 1 Trial of LYR-210 in Chronic Rhinosinusitis (CRS) Expected in May -- -- Phase 3 Results from ENLIGHTEN 1 Trial of LYR-210 in Chronic Rhinosinusitis (CRS) Expected in May --

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3 'Buy-Rated' Biotech Stocks Under $10

Today, we look at three small-cap biotech/biopharma stocks. All three have attractive risk/reward profiles and potential catalysts on the horizon. An investment synopsis on all three firms is presented in the paragraphs below.

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Lyra Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WATERTOWN, Mass., April 26, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (the “Company” or “Lyra”), a clinical-stage biotech developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today announced that it has granted non-qualified stock options to purchase a total of 78,400 shares of Lyra Therapeutics common stock to 16 new non-executive employees as an inducement material to their acceptance of employment with Lyra Therapeutics. The employment inducement awards were approved by Lyra's independent directors serving on its Compensation Committee and granted under Lyra's 2022 Employment Inducement Award Plan, as amended, and related form of stock option agreement in accordance with Nasdaq Listing Rule 5635(c)(4).

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Lyra Therapeutics (LYRA) Soars 6.5%: Is Further Upside Left in the Stock?

Lyra Therapeutics (LYRA) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions could translate into further price increase in the near term.

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Lyra Therapeutics (LYRA) Is a Great Choice for 'Trend' Investors, Here's Why

Lyra Therapeutics (LYRA) could be a solid choice for shorter-term investors looking to capitalize on the recent price trend in fundamentally sound stocks. It is one of the many stocks that passed through our shorter-term trading strategy-based screen.

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Wall Street Analysts See a 101.81% Upside in Lyra Therapeutics (LYRA): Can the Stock Really Move This High?

The consensus price target hints at a 101.8% upside potential for Lyra Therapeutics (LYRA). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term.

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Lyra Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update

-- Data from ENLIGHTEN I Pivotal Phase 3 Trial of LYR-210 in Chronic Rhinosinusitis (CRS) Anticipated Q2 2024 -- WATERTOWN, Mass., March 21, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory nasal inserts for the treatment of chronic rhinosinusitis (CRS), today reported its financial results for the fourth quarter and full year ended December 31, 2023 and provided a corporate update.

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Here's Why Momentum in Lyra Therapeutics, Inc. (LYRA) Should Keep going

Lyra Therapeutics, Inc. (LYRA) made it through our "Recent Price Strength" screen and could be a great choice for investors looking to make a profit from stocks that are currently on the move.

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Lyra Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

WATERTOWN, Mass., March 01, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory nasal inserts for the treatment of chronic rhinosinusitis (CRS), today announced that it has granted non-qualified stock options to purchase a total of 119,200 shares of Lyra common stock to 18 new non-executive employees as an inducement material to their acceptance of employment with Lyra. The employment inducement awards were approved by Lyra's independent directors serving on its Compensation Committee and granted under the Company's 2022 Inducement Award Plan, as amended, and related form of stock option agreement in accordance with Nasdaq Listing Rule 5635(c)(4).

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5 Small Drug Stocks to Buy From a Rebounding Industry

Innovation is expected to continue to drive growth of the Medical-Drugs industry. UTHR, ESPR, HRTX, LYRA and ALDX may prove to be good additions to one's portfolio.

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Strength Seen in Lyra Therapeutics, Inc. (LYRA): Can Its 6.9% Jump Turn into More Strength?

Lyra Therapeutics, Inc. (LYRA) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road.

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What Makes Lyra Therapeutics, Inc. (LYRA) a Good Fit for 'Trend Investing'

Lyra Therapeutics, Inc. (LYRA) made it through our "Recent Price Strength" screen and could be a great choice for investors looking to make a profit from stocks that are currently on the move.

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4 Drug Stocks Rising More Than 40% in 2023 With Room to Grow

Novo Nordisk (NVO), Journey Medical Corporation (DERM), Lyra Therapeutics (LYRA) and Fusion Pharmaceuticals (FUSN) have returned 40% or higher year to date and have room for more growth in 2024.

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5 Small Drug Stocks to Buy on Hopes of Better Prospects in the New Year

Innovation is expected to continue driving growth in the Medical-Drugs industry. DERM, LYRA, AUPH, ALPN and HARP may prove to be good additions to one's portfolio.

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Lyra Therapeutics Reports Third Quarter 2023 Financial Results and Provides Corporate Update

– Additional Phase 2 BEACON trial CT scan data demonstrated statistically significant improvement in sinus opacification with LYR-220 and provided radiological evidence of improvement in chronic rhinosinusitis (CRS) patients who have had prior ethmoid sinus surgery –

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Lyra Therapeutics to Participate in Upcoming Investor Conferences

WATERTOWN, Mass., Nov. 07, 2023 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA), a clinical-stage biotechnology company developing innovative therapies for the localized treatment of chronic rhinosinusitis (CRS), today announced that Maria Palasis, Ph.D., President and Chief Executive Officer, will participate in the following investor conferences in November:

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Lyra Therapeutics Announces Appointment of Ronan O'Brien as Chief Legal Officer

WATERTOWN, Mass., Oct. 16, 2023 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing innovative therapies for the localized treatment of chronic rhinosinusitis (“CRS”), today announced the appointment of Ronan O'Brien, as Chief Legal Officer, effective October 16, 2023.

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Lyra Therapeutics: Hold For Phase 3 Topline

Lyra Therapeutics has two product candidates in clinical trials for Chronic rhinosinusitis (CRS) patients. Both candidates, LYR-210 and LYR-220, show promising efficacy data, with LYR-210 in phase 3 trials and LYR-220 in phase 2 trials. Lyra has a market cap of $190mn and enough cash to sustain operations until 2025, but more cash would be desirable.

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Related Metrics

Explore detailed financial metrics and analysis for LYRA.